• Expert consensus on re-irradiation for current glioma 

      Krauze, Andra; Attia, Albert; Braunstein, Steve; Chan, Michael; Combs, Stephanie E; Fietkau, Rainer; Fiveash, John; Flickinger, John; Grosu, Anca-Ligia; Howard, Steven; Nieder, Carsten; Niyazi, Maximilian; Rowe, Lindsay; Smart, Dee Dee; Tsien, Christina; Camphausen, Kevin (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-01)
      Purpose:<br>To investigate radiation oncologists’ opinions on important considerations to offering re-irradiation (re-RT) as a treatment option for recurrent glioma.<br>Materials and methods:<br>A survey was conducted with 13 radiation oncologists involved in the care of central nervous system tumor patients. The survey was comprised of 49 questions divided into 2 domains: a demographic section (10 ...
    • Hippocampus-avoidance whole-brain radiation therapy with a simultaneous integrated boost for multiple brain metastases 

      Popp, Ilinca; Rau, Stephan; Hintz, Mandy; Schneider, Julius; Bilger, Angelika; Fennell, Jamina Tara; Heiland, Dieter Henrik; Rothe, Thomas; Egger, Karl; Nieder, Carsten; Urbach, Horst; Grosu, Anca-Ligia (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-06)
      <i>Background</i> - The current study was aimed at investigating the feasibility of hippocampus‐avoidance whole‐brain radiation therapy with a simultaneous integrated boost (HA‐WBRT+SIB) for metastases and at assessing tumor control in comparison with conventional whole‐brain radiation therapy (WBRT) in patients with multiple brain metastases.<p> <p><i>Methods</i> - Between August 2012 and December ...
    • Local Control and overall survival after frameless radiosurgery: A single center experience 

      Bilger, Angelika; Frenzel, Florian; Oehlke, Oliver; Wiehle, Rolf; Milanovic, Dusan; Prokic, Vesna; Nieder, Carsten; Grosu, Anca-Ligia (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-06)
      <p><i>Introduction</i> Stereotactic radiosurgery (SRS) has been increasingly advocated for 1–3 small brain metastases. The goal of this study was to evaluate the clinical results in patients with brain metastases treated with LINAC-based SRS using a thermoplastic mask (non-invasive fixation system) and Image-Guided Radiotherapy (IGRT).</p> <p><i>Material and Methods</i> In this single-institution ...
    • Local control and possibility of tailored salvage after hypofractionated stereotactic radiotherapy of the cavity after brain metastases resection 

      Bilger, Angelika; Bretzinger, Eva; Fennell, Jamina; Nieder, Carsten; Lorenz, Hannah; Oehlke, Oliver; Grosu, Anca-Ligia; Specht, Hanno M.; Combs, Stephanie E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-09)
      In patients undergoing surgical resection of brain metastases, the risk of local recurrence remains high. Adjuvant whole brain radiation therapy (WBRT) can reduce the risk of local relapse but fails to improve overall survival. At two tertiary care centers in Germany, a retrospective study was performed to evaluate the role of hypofractionated stereotactic radiotherapy (HFSRT) in patients with brain ...
    • Radiotherapy for nonagenarians: The value of biological versus chronological age 

      Sprave, Tanja; Rühle, Alexander; Stoian, Raluca; Weber, Alina; Zamboglou, Constantinos; Nieder, Carsten; Grosu, Anca-Ligia; Nicolay, Nils H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-19)
      <i>Background</i> - The number of nonagenarian cancer patients (≥ 90 years) is continuously increasing, and radiotherapy is performed in a relevant proportion of patients, as surgery and chemotherapy are often not feasible for these patients. However, the evidence regarding the feasibility and treatment outcomes after radiotherapy for this patient group is very limited.<p> <p><i>Methods</i> - All ...
    • Scientific impact of studies published in temporarily available radiation oncology journals: a citation analysis 

      Nieder, Carsten; Geinitz, Hans; Andratschke, Nikolaus H.; Grosu, Anca-Ligia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-24)
      The purpose of this study was to review all articles published in two temporarily available radiation oncology journals (Radiation Oncology Investigations, Journal of Radiosurgery) in order to evaluate their scientific impact. From several potential measures of impact and relevance of research, we selected article citation rate because landmark or practice-changing research is likely to be cited ...